What is the underlying mechanism of propulsion in the digestive system, and how is motility stimulated? How are some newer pharmacotherapies looking to target serotonin to treat conditions such as IBS and constipation? Dr. Jack Grider, professor in the department of medicine, division of gastroenterology at the Virginia Commonwealth University School of Medicine, talks about future pharmacotherapy directions that either suppress or encourage motility in the digestive system. Hosted by Dr. Mark DeLegge.